Telomere-Binding Protein TPP1 Modulates Telomere Homeostasis and Confers Radioresistance to Human Colorectal Cancer Cells

BACKGROUND: Radiotherapy is one of the major therapeutic strategies in cancer treatment. The telomere-binding protein TPP1 is an important component of the shelterin complex at mammalian telomeres. Our previous reports showed that TPP1 expression was elevated in radioresistant cells, but the exact e...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Lei, Wang, Wenbo, Hu, Liu, Yang, Xiaoxi, Zhong, Juan, Li, Zheng, Yang, Hui, Lei, Han, Yu, Haijun, Liao, ZhengKai, Zhou, Fuxiang, Xie, Conghua, Zhou, Yunfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834294/
https://www.ncbi.nlm.nih.gov/pubmed/24260532
http://dx.doi.org/10.1371/journal.pone.0081034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834294/
https://www.ncbi.nlm.nih.gov/pubmed/24260532
http://dx.doi.org/10.1371/journal.pone.0081034

Ejemplares similares