Telomere-Binding Protein TPP1 Modulates Telomere Homeostasis and Confers Radioresistance to Human Colorectal Cancer Cells

BACKGROUND: Radiotherapy is one of the major therapeutic strategies in cancer treatment. The telomere-binding protein TPP1 is an important component of the shelterin complex at mammalian telomeres. Our previous reports showed that TPP1 expression was elevated in radioresistant cells, but the exact e...

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Detalles Bibliográficos
Autores principales: Yang, Lei, Wang, Wenbo, Hu, Liu, Yang, Xiaoxi, Zhong, Juan, Li, Zheng, Yang, Hui, Lei, Han, Yu, Haijun, Liao, ZhengKai, Zhou, Fuxiang, Xie, Conghua, Zhou, Yunfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834294/
https://www.ncbi.nlm.nih.gov/pubmed/24260532
http://dx.doi.org/10.1371/journal.pone.0081034

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