Paraventricular Nucleus Sim1 Neuron Ablation Mediated Obesity Is Resistant to High Fat Diet

Single minded 1 (SIM1) is a transcription factor involved in brain patterning and control of energy balance. In humans, haploinsufficiency of SIM1 causes early-onset obesity. Mice deficient in the homologous gene, SIM1, also exhibit early onset obesity and increased sensitivity to a high fat diet. S...

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Detalles Bibliográficos
Autores principales: Xi, Dong, Roizen, Jeff, Lai, Meizan, Gandhi, Nilay, Kublaoui, Bassil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834298/
https://www.ncbi.nlm.nih.gov/pubmed/24260538
http://dx.doi.org/10.1371/journal.pone.0081087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834298/
https://www.ncbi.nlm.nih.gov/pubmed/24260538
http://dx.doi.org/10.1371/journal.pone.0081087

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