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A-Site mRNA Cleavage Is Not Required for tmRNA-Mediated ssrA-Peptide Tagging
In Escherichia coli, prolonged translational arrest allows mRNA degradation into the A site of stalled ribosomes. The enzyme that cleaves the A-site codon is not known, but its activity requires RNase II to degrade mRNA downstream of the ribosome. This A-site mRNA cleavage process is thought to func...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834316/ https://www.ncbi.nlm.nih.gov/pubmed/24260569 http://dx.doi.org/10.1371/journal.pone.0081319 |