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Mitochondrial Dysfunction Leads to Deconjugation of Quercetin Glucuronides in Inflammatory Macrophages

Dietary flavonoids, such as quercetin, have long been recognized to protect blood vessels from atherogenic inflammation by yet unknown mechanisms. We have previously discovered the specific localization of quercetin-3-O-glucuronide (Q3GA), a phase II metabolite of quercetin, in macrophage cells in t...

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Detalles Bibliográficos
Autores principales: Ishisaka, Akari, Kawabata, Kyuichi, Miki, Satomi, Shiba, Yuko, Minekawa, Shoko, Nishikawa, Tomomi, Mukai, Rie, Terao, Junji, Kawai, Yoshichika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834324/
https://www.ncbi.nlm.nih.gov/pubmed/24260490
http://dx.doi.org/10.1371/journal.pone.0080843