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Micronucleus Test of Picrorrhiza Rhizoma Aqueous Extract in Bone Marrow Cells of Male ICR Mice

In this research, the genotoxic effect of Picrorrhiza Rhizoma (PR) aqueous extract was evaluated using the mouse micronucleus test. PR extract was administered once a day for 2 continuous days by oral gavage to male ICR mice at doses of 2000, 1000 and 500 mg/kg. Cyclophosphamide was used as a known...

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Detalles Bibliográficos
Autores principales: Chung, In-Kwon, Cheon, Woo-Hyun, Ku, Sae-Kwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Toxicology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834366/
https://www.ncbi.nlm.nih.gov/pubmed/24278560
http://dx.doi.org/10.5487/TR.2011.27.2.119