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Embryotoxicity and Toxicokinetics of the Antimalarial Artesunate in Rats

This study was conducted to investigate the potential embryo-fetal toxicity and toxicokinetics of the antimalarial agent artesunate (ARTS) in Sprague-Dawley rats. Pregnant rats were administered ARTS daily from gestational day 6~15 via oral gavage, at test doses of 0, 2, 4, or 8 mg/kg (22 females pe...

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Detalles Bibliográficos
Autores principales: Chung, Moon-Koo, Yu, Wook-Joon, Lee, Jin-Soo, Lee, Jong-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Toxicology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834439/
https://www.ncbi.nlm.nih.gov/pubmed/24278626
http://dx.doi.org/10.5487/TR.2013.29.1.027