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Evaluation of Embryotoxic Potential of Olaquindox and Vitamin A in Micromass Culture and in Rats

Limb bud (LB) and central nerve system (CNS) cells were prepared from 12.5 day old pregnant female Crj:CD (SD) rats and treated with olaquindox and vitamin A. Cytotoxicity and inhibition on differentiation were measured in each cell. Three doses of olaquindox (4, 21 and 100 mgkg) , and 0.2 and 75 mg...

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Detalles Bibliográficos
Autores principales: Kang, Hwan Goo, Ku, Hyun Ok, Jeong, Sang Hee, Cho, Joon Hyoung, Son, Seong Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Toxicology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834482/
https://www.ncbi.nlm.nih.gov/pubmed/24278526
http://dx.doi.org/10.5487/TR.2010.26.3.209