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Human Immunodeficiency Virus and Heparan Sulfate: From Attachment to Entry Inhibition

By targeting cells that provide protection against infection, HIV-1 causes acquired immunodeficiency syndrome. Infection starts when gp120, the viral envelope glycoprotein, binds to CD4 and to a chemokine receptor usually CCR5 or CXCR4. As many microorganisms, HIV-1 also interacts with heparan sulfa...

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Detalles Bibliográficos
Autores principales: Connell, Bridgette J., Lortat-Jacob, Hugues
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834540/
https://www.ncbi.nlm.nih.gov/pubmed/24312095
http://dx.doi.org/10.3389/fimmu.2013.00385