HMGB1 Acts in Synergy with Lipopolysaccharide in Activating Rheumatoid Synovial Fibroblasts via p38 MAPK and NF-κB Signaling Pathways

Synovial fibroblasts (SF) play a central role in the inflammatory and destructive process in rheumatoid arthritis (RA). High-mobility group box chromosomal protein 1 (HMGB1) or lipopolysaccharide (LPS) alone failed to induce significant changes in proliferation of cultured SF from RA patients, but p...

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Detalles Bibliográficos
Autores principales: He, Zheng-Wen, Qin, Yang-Hua, Wang, Zhi-Wei, Chen, Yan, Shen, Qian, Dai, Sheng-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834620/
https://www.ncbi.nlm.nih.gov/pubmed/24302816
http://dx.doi.org/10.1155/2013/596716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834620/
https://www.ncbi.nlm.nih.gov/pubmed/24302816
http://dx.doi.org/10.1155/2013/596716

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