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Do Bayesian adaptive trials offer advantages for comparative effectiveness research? Protocol for the RE-ADAPT study

BACKGROUND: Randomized clinical trials, particularly for comparative effectiveness research (CER), are frequently criticized for being overly restrictive or untimely for health-care decision making. PURPOSE: Our prospectively designed REsearch in ADAptive methods for Pragmatic Trials (RE-ADAPT) stud...

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Detalles Bibliográficos
Autores principales: Connor, Jason T, Luce, Bryan R, Broglio, Kristine R, Ishak, K Jack, Mullins, C Daniel, Vanness, David J, Fleurence, Rachael, Saunders, Elijah, Davis, Barry R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834735/
https://www.ncbi.nlm.nih.gov/pubmed/23983160
http://dx.doi.org/10.1177/1740774513497293