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A single channel mutation alters agonist efficacy at 5-HT(3)A and 5-HT(3)AB receptors
BACKGROUND AND PURPOSE: 5-HT(3) receptors are composed of 5-HT(3)A subunits (homomeric receptors), or combinations of 5-HT(3)A and other 5-HT(3) receptor subunits (heteromeric receptors, the best studied of which are 5-HT(3)AB receptors). Here we explore the effects of partial agonists at 5-HT(3)A a...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834762/ https://www.ncbi.nlm.nih.gov/pubmed/23822584 http://dx.doi.org/10.1111/bph.12287 |