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A single channel mutation alters agonist efficacy at 5-HT(3)A and 5-HT(3)AB receptors

BACKGROUND AND PURPOSE: 5-HT(3) receptors are composed of 5-HT(3)A subunits (homomeric receptors), or combinations of 5-HT(3)A and other 5-HT(3) receptor subunits (heteromeric receptors, the best studied of which are 5-HT(3)AB receptors). Here we explore the effects of partial agonists at 5-HT(3)A a...

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Detalles Bibliográficos
Autores principales:	Thompson, A J, Lummis, S C R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2013
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834762/ https://www.ncbi.nlm.nih.gov/pubmed/23822584 http://dx.doi.org/10.1111/bph.12287

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