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HMCan: a method for detecting chromatin modifications in cancer samples using ChIP-seq data

Motivation: Cancer cells are often characterized by epigenetic changes, which include aberrant histone modifications. In particular, local or regional epigenetic silencing is a common mechanism in cancer for silencing expression of tumor suppressor genes. Though several tools have been created to en...

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Detalles Bibliográficos
Autores principales: Ashoor, Haitham, Hérault, Aurélie, Kamoun, Aurélie, Radvanyi, François, Bajic, Vladimir B., Barillot, Emmanuel, Boeva, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834794/
https://www.ncbi.nlm.nih.gov/pubmed/24021381
http://dx.doi.org/10.1093/bioinformatics/btt524