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HMCan: a method for detecting chromatin modifications in cancer samples using ChIP-seq data
Motivation: Cancer cells are often characterized by epigenetic changes, which include aberrant histone modifications. In particular, local or regional epigenetic silencing is a common mechanism in cancer for silencing expression of tumor suppressor genes. Though several tools have been created to en...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834794/ https://www.ncbi.nlm.nih.gov/pubmed/24021381 http://dx.doi.org/10.1093/bioinformatics/btt524 |