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Both mature miR-17-5p and passenger strand miR-17-3p target TIMP3 and induce prostate tumor growth and invasion

MicroRNAs (miRNA) precursor (pre-miRNA) molecules can be processed to release a miRNA/miRNA* duplex. In the canonical model of miRNA biogenesis, one strand of the duplex is thought to be the biologically active miRNA, whereas the other strand is thought to be inactive and degraded as a carrier or pa...

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Detalles Bibliográficos
Autores principales: Yang, Xiangling, Du, William W., Li, Haoran, Liu, Fengqiong, Khorshidi, Anna, Rutnam, Zina Jeyapalan, Yang, Burton B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834805/
https://www.ncbi.nlm.nih.gov/pubmed/23990326
http://dx.doi.org/10.1093/nar/gkt680