Replisome stall events have shaped the distribution of replication origins in the genomes of yeasts

During S phase, the entire genome must be precisely duplicated, with no sections of DNA left unreplicated. Here, we develop a simple mathematical model to describe the probability of replication failing due to the irreversible stalling of replication forks. We show that the probability of complete g...

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Detalles Bibliográficos
Autores principales: Newman, Timothy J., Mamun, Mohammed A., Nieduszynski, Conrad A., Blow, J. Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834809/
https://www.ncbi.nlm.nih.gov/pubmed/23963700
http://dx.doi.org/10.1093/nar/gkt728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834809/
https://www.ncbi.nlm.nih.gov/pubmed/23963700
http://dx.doi.org/10.1093/nar/gkt728

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