Structural basis for Z-DNA binding and stabilization by the zebrafish Z-DNA dependent protein kinase PKZ

The RNA-dependent protein kinase PKR plays a central role in the antiviral defense of vertebrates by shutting down protein translation upon detection of viral dsRNA in the cytoplasm. In some teleost fish, PKZ, a homolog of PKR, performs the same function, but surprisingly, instead of dsRNA binding d...

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Detalles Bibliográficos
Autores principales: de Rosa, Matteo, Zacarias, Sonia, Athanasiadis, Alekos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834819/
https://www.ncbi.nlm.nih.gov/pubmed/23975196
http://dx.doi.org/10.1093/nar/gkt743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834819/
https://www.ncbi.nlm.nih.gov/pubmed/23975196
http://dx.doi.org/10.1093/nar/gkt743

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