Negative regulation of mitochondrial transcription by mitochondrial topoisomerase I

Mitochondrial topoisomerase I is a genetically distinct mitochondria-dedicated enzyme with a crucial but so far unknown role in the homeostasis of mitochondrial DNA metabolism. Here, we present data suggesting a negative regulatory function in mitochondrial transcription or transcript stability. Def...

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Detalles Bibliográficos
Autores principales: Sobek, Stefan, Dalla Rosa, Ilaria, Pommier, Yves, Bornholz, Beatrice, Kalfalah, Faiza, Zhang, Hongliang, Wiesner, Rudolf J., von Kleist-Retzow, Jürgen-Christoph, Hillebrand, Frank, Schaal, Heiner, Mielke, Christian, Christensen, Morten O., Boege, Fritz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834834/
https://www.ncbi.nlm.nih.gov/pubmed/23982517
http://dx.doi.org/10.1093/nar/gkt768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834834/
https://www.ncbi.nlm.nih.gov/pubmed/23982517
http://dx.doi.org/10.1093/nar/gkt768

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