Cargando…

Crystal structure of RuvC resolvase in complex with Holliday junction substrate

The key intermediate in genetic recombination is the Holliday junction (HJ), a four-way DNA structure. At the end of recombination, HJs are cleaved by specific nucleases called resolvases. In Gram-negative bacteria, this cleavage is performed by RuvC, a dimeric endonuclease that belongs to the retro...

Descripción completa

Detalles Bibliográficos
Autores principales: Górecka, Karolina M., Komorowska, Weronika, Nowotny, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834835/
https://www.ncbi.nlm.nih.gov/pubmed/23980027
http://dx.doi.org/10.1093/nar/gkt769