Type II cGMP-dependent protein kinase inhibits epidermal growth factor-induced phosphatidylinositol-3-kinase/Akt signal transduction in gastric cancer cells

Our previous study revealed that Type II cGMP-dependent protein kinase (PKG II) inhibits epidermal growth factor (EGF)-induced MAPK/ERK and MAPK/JNK-mediated signal transduction through the inhibition of the phosphorylation/activation of the EGF receptor (EGFR). As EGFR also mediates several other s...

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Detalles Bibliográficos
Autores principales: WU, MIN, CHEN, YONGCHANG, JIANG, LU, LI, YUEYING, LAN, TING, WANG, YING, QIAN, HAI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834871/
https://www.ncbi.nlm.nih.gov/pubmed/24273605
http://dx.doi.org/10.3892/ol.2013.1630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834871/
https://www.ncbi.nlm.nih.gov/pubmed/24273605
http://dx.doi.org/10.3892/ol.2013.1630

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