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A fully caninised anti-NGF monoclonal antibody for pain relief in dogs

BACKGROUND: Monoclonal antibodies are a major class of biological therapies in human medicine but have not yet been successfully applied to veterinary species. We have developed a novel approach, PETisation, to rapidly convert antibodies for use in veterinary species. As an example, anti-nerve growt...

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Detalles Bibliográficos
Autores principales: Gearing, David P, Virtue, Elena R, Gearing, Robert P, Drew, Alexander C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834884/
https://www.ncbi.nlm.nih.gov/pubmed/24206926
http://dx.doi.org/10.1186/1746-6148-9-226