Design of Skin Penetration Enhancers Using Replacement Methods for the Selection of the Molecular Descriptors

Transdermal delivery of certain drugs is challenging because of skin barrier resistance. This study focuses on the implementation of feature-selection algorithms to design chemical penetration enhancers. A database, consisting of 145 polar and nonpolar chemicals, was chosen for the investigation. Re...

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Detalles Bibliográficos
Autores principales: Simon, Laurent, Abdelmalek, Beshoy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834920/
https://www.ncbi.nlm.nih.gov/pubmed/24300295
http://dx.doi.org/10.3390/pharmaceutics4030343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834920/
https://www.ncbi.nlm.nih.gov/pubmed/24300295
http://dx.doi.org/10.3390/pharmaceutics4030343

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