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Design of Skin Penetration Enhancers Using Replacement Methods for the Selection of the Molecular Descriptors
Transdermal delivery of certain drugs is challenging because of skin barrier resistance. This study focuses on the implementation of feature-selection algorithms to design chemical penetration enhancers. A database, consisting of 145 polar and nonpolar chemicals, was chosen for the investigation. Re...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834920/ https://www.ncbi.nlm.nih.gov/pubmed/24300295 http://dx.doi.org/10.3390/pharmaceutics4030343 |