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Overexpression of MMP-7 increases collagen 1A2 in the aging kidney

The percentage of the U.S. population over 65 is rapidly increasing, as is the incidence of chronic kidney disease (CKD). The kidney is susceptible to age-dependent alterations in structure, specifically tubulointerstitial fibrosis that leads to CKD. Matrix metalloproteinases (MMPs) were initially c...

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Detalles Bibliográficos
Autores principales: Ślusarz, Anna, Nichols, LaNita A, Grunz-Borgmann, Elizabeth A, Chen, Gang, Akintola, Adebayo D, Catania, Jeffery M, Burghardt, Robert C, Trzeciakowski, Jerome P, Parrish, Alan R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834982/
https://www.ncbi.nlm.nih.gov/pubmed/24273653
http://dx.doi.org/10.1002/phy2.90