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Focal axonal swellings and associated ultrastructural changes attenuate conduction velocity in central nervous system axons: a computer modeling study

The constancy of action potential conduction in the central nervous system (CNS) relies on uniform axon diameter coupled with fidelity of the overlying myelin providing high-resistance, low capacitance insulation. Whereas the effects of demyelination on conduction have been extensively studied/model...

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Detalles Bibliográficos
Autores principales: Kolaric, Katarina V, Thomson, Gemma, Edgar, Julia M, Brown, Angus M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835014/
https://www.ncbi.nlm.nih.gov/pubmed/24303138
http://dx.doi.org/10.1002/phy2.59