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Focal axonal swellings and associated ultrastructural changes attenuate conduction velocity in central nervous system axons: a computer modeling study
The constancy of action potential conduction in the central nervous system (CNS) relies on uniform axon diameter coupled with fidelity of the overlying myelin providing high-resistance, low capacitance insulation. Whereas the effects of demyelination on conduction have been extensively studied/model...
Autores principales: | Kolaric, Katarina V, Thomson, Gemma, Edgar, Julia M, Brown, Angus M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835014/ https://www.ncbi.nlm.nih.gov/pubmed/24303138 http://dx.doi.org/10.1002/phy2.59 |
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