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Nrf2 and NF-κB and Their Concerted Modulation in Cancer Pathogenesis and Progression

Reactive oxygen species, produced by oxidative stress, are implicated in the initiation, promotion, and malignant conversion of carcinogenesis through activation/suppression of redox-sensitive transcription factors. NF-E2-related factor 2 (Nrf2) encodes for antioxidant and general cytoprotection gen...

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Detalles Bibliográficos
Autores principales: Bellezza, Ilaria, Mierla, Anna Lisa, Minelli, Alba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835087/
https://www.ncbi.nlm.nih.gov/pubmed/24281078
http://dx.doi.org/10.3390/cancers2020483