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Liver protective effect of ursodeoxycholic acid includes regulation of ADAM17 activity

BACKGROUND: Ursodeoxycholic acid (UDCA) is used to treat primary biliary cirrhosis, intrahepatic cholestasis, and other cholestatic conditions. Although much has been learned about the molecular basis of the disease pathophysiology, our understanding of the effects of UDCA remains unclear. Possibly...

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Detalles Bibliográficos
Autores principales: Buryova, Halka, Chalupsky, Karel, Zbodakova, Olga, Kanchev, Ivan, Jirouskova, Marketa, Gregor, Martin, Sedlacek, Radislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835136/
https://www.ncbi.nlm.nih.gov/pubmed/24172289
http://dx.doi.org/10.1186/1471-230X-13-155