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PERK‐eIF2α‐ATF4‐CHOP Signaling Contributes to TNFα‐Induced Vascular Calcification

BACKGROUND: Vascular calcification is a common feature in patients with chronic kidney disease (CKD). CKD increases serum levels of tumor necrosis factor‐α (TNFα), a critical mediator of vascular calcification. However, the molecular mechanism by which TNFα promotes CKD‐dependent vascular calcificat...

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Detalles Bibliográficos
Autores principales: Masuda, Masashi, Miyazaki‐Anzai, Shinobu, Levi, Moshe, Ting, Tabitha C., Miyazaki, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835225/
https://www.ncbi.nlm.nih.gov/pubmed/24008080
http://dx.doi.org/10.1161/JAHA.113.000238