Targeting Nuclear Import Shuttles, Importins/Karyopherins alpha by a Peptide Mimicking the NFκB1/p50 Nuclear Localization Sequence

BACKGROUND: We recently reported that a bifunctional nuclear transport modifier (NTM), cSN50.1 peptide, reduced atherosclerosis, plasma cholesterol, triglycerides, and glucose along with liver fat and inflammatory markers, in a murine model of familial hypercholesterolemia. We determined that cSN50....

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Detalles Bibliográficos
Autores principales: Zienkiewicz, Jozef, Armitage, Amy, Hawiger, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835248/
https://www.ncbi.nlm.nih.gov/pubmed/24042087
http://dx.doi.org/10.1161/JAHA.113.000386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835248/
https://www.ncbi.nlm.nih.gov/pubmed/24042087
http://dx.doi.org/10.1161/JAHA.113.000386

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