Abnormal Calcium Cycling and Cardiac Arrhythmias Associated With the Human Ser96Ala Genetic Variant of Histidine‐Rich Calcium‐Binding Protein

BACKGROUND: A human genetic variant (Ser96Ala) in the sarcoplasmic reticulum (SR) histidine‐rich Ca(2+)‐binding (HRC) protein has been linked to ventricular arrhythmia and sudden death in dilated cardiomyopathy. However, the precise mechanisms affecting SR function and leading to arrhythmias remain...

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Detalles Bibliográficos
Autores principales: Singh, Vivek P., Rubinstein, Jack, Arvanitis, Demetrios A., Ren, Xiaoping, Gao, Xiaoqian, Haghighi, Kobra, Gilbert, Mark, Iyer, Venkat R., Kim, Do Han, Cho, Chunghee, Jones, Keith, Lorenz, John N., Armstrong, Clara F., Wang, Hong‐Sheng, Gyorke, Sandor, Kranias, Evangelia G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835262/
https://www.ncbi.nlm.nih.gov/pubmed/24125847
http://dx.doi.org/10.1161/JAHA.113.000460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835262/
https://www.ncbi.nlm.nih.gov/pubmed/24125847
http://dx.doi.org/10.1161/JAHA.113.000460

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