Tau Causes Synapse Loss without Disrupting Calcium Homeostasis in the rTg4510 Model of Tauopathy

Neurofibrillary tangles (NFTs) of tau are one of the defining hallmarks of Alzheimer’s disease (AD), and are closely associated with neuronal degeneration. Although it has been suggested that calcium dysregulation is important to AD pathogenesis, few studies have probed the link between calcium home...

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Detalles Bibliográficos
Autores principales: Kopeikina, Katherine J., Wegmann, Susanne, Pitstick, Rose, Carlson, George A., Bacskai, Brian J., Betensky, Rebecca A., Hyman, Bradley T., Spires-Jones, Tara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835324/
https://www.ncbi.nlm.nih.gov/pubmed/24278327
http://dx.doi.org/10.1371/journal.pone.0080834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835324/
https://www.ncbi.nlm.nih.gov/pubmed/24278327
http://dx.doi.org/10.1371/journal.pone.0080834

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