Helicase-Like Transcription Factor (Hltf) Regulates G2/M Transition, Wt1/Gata4/Hif-1a Cardiac Transcription Networks, and Collagen Biogenesis

HLTF/Hltf regulates transcription, remodels chromatin, and coordinates DNA damage repair. Hltf is expressed in mouse brain and heart during embryonic and postnatal development. Silencing Hltf is semilethal. Seventy-four percent of congenic C57BL/6J Hltf knockout mice died, 75% within 12-24 hours of...

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Detalles Bibliográficos
Autores principales: Helmer, Rebecca A., Martínez-Zaguilán, Raul, Dertien, Janet S., Fulford, Candra, Foreman, Oded, Peiris, Vasum, Chilton, Beverly S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835564/
https://www.ncbi.nlm.nih.gov/pubmed/24278285
http://dx.doi.org/10.1371/journal.pone.0080461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835564/
https://www.ncbi.nlm.nih.gov/pubmed/24278285
http://dx.doi.org/10.1371/journal.pone.0080461

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