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Chemoresistance to Concanamycin A1 in Human Oral Squamous Cell Carcinoma Is Attenuated by an HDAC Inhibitor Partly via Suppression of Bcl-2 Expression

V-ATPase is involved in the acidification of the microenvironment around/in solid tumors, such as oral squamous cell carcinoma (OSCC). V-ATPase is thought to induce tumor invasion and multi-drug resistance in several malignant tumors, and it also contributes to maintaining the intracellular pH under...

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Detalles Bibliográficos
Autores principales: Kiyoshima, Tamotsu, Yoshida, Hisato, Wada, Hiroko, Nagata, Kengo, Fujiwara, Hiroaki, Kihara, Makiko, Hasegawa, Kana, Someya, Hirotaka, Sakai, Hidetaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835574/
https://www.ncbi.nlm.nih.gov/pubmed/24278362
http://dx.doi.org/10.1371/journal.pone.0080998