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Targeting of Arenavirus RNA Synthesis by a Carboxamide-Derivatized Aromatic Disulfide with Virucidal Activity

Several arenaviruses can cause severe hemorrhagic fever (HF) in humans, representing a public health threat in endemic areas of Africa and South America. The present study characterizes the potent virucidal activity of the carboxamide-derivatized aromatic disulfide NSC4492, an antiretroviral zinc fi...

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Detalles Bibliográficos
Autores principales: Sepúlveda, Claudia S., García, Cybele C., Levingston Macleod, Jesica M., López, Nora, Damonte, Elsa B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835668/
https://www.ncbi.nlm.nih.gov/pubmed/24278404
http://dx.doi.org/10.1371/journal.pone.0081251