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The antioxidant effects of the flavonoids rutin and quercetin inhibit oxaliplatin-induced chronic painful peripheral neuropathy

BACKGROUND: Oxaliplatin, the third-generation platinum compound, has evolved as one of the most important therapeutic agents in colorectal cancer chemotherapy. The main limiting factor in oxaliplatin treatment is painful neuropathy that is difficult to treat. This side effect has been studied for se...

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Detalles Bibliográficos
Autores principales: Azevedo, Maria Isabel, Pereira, Anamaria Falcão, Nogueira, Ricardo Braz, Rolim, Flávio Esmeraldo, Brito, Gerly AC, Wong, Deysi Viviana T, Lima-Júnior, Roberto CP, de Albuquerque Ribeiro, Ronaldo, Vale, Mariana Lima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835704/
https://www.ncbi.nlm.nih.gov/pubmed/24152430
http://dx.doi.org/10.1186/1744-8069-9-53