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Angiopoietin-Like 3 Induces Podocyte F-Actin Rearrangement through Integrin α (V) β (3)/FAK/PI3K Pathway-Mediated Rac1 Activation
Glomerular podocytes are highly differentiated cells whose foot processes, which are mainly maintained by the architecture of actin filaments, have a unique morphology. A rearrangement of F-actin in podocytes causes changes in their motility that involve foot process effacement and proteinuria in gl...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835706/ https://www.ncbi.nlm.nih.gov/pubmed/24294595 http://dx.doi.org/10.1155/2013/135608 |