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Angiopoietin-Like 3 Induces Podocyte F-Actin Rearrangement through Integrin α (V) β (3)/FAK/PI3K Pathway-Mediated Rac1 Activation

Glomerular podocytes are highly differentiated cells whose foot processes, which are mainly maintained by the architecture of actin filaments, have a unique morphology. A rearrangement of F-actin in podocytes causes changes in their motility that involve foot process effacement and proteinuria in gl...

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Detalles Bibliográficos
Autores principales: Lin, Yi, Rao, Jia, Zha, Xi-liang, Xu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835706/
https://www.ncbi.nlm.nih.gov/pubmed/24294595
http://dx.doi.org/10.1155/2013/135608

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