Thioredoxin-interacting protein regulates insulin transcription through microRNA-204

Beta-cell dysfunction and impaired insulin production are hallmarks of diabetes(1), but despite the growing diabetes epidemic the molecular mechanisms involved have remained unclear. We identified thioredoxin-interacting protein (TXNIP), a cellular redox regulator, as a critical factor involved in b...

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Detalles Bibliográficos
Autores principales: Xu, Guanlan, Chen, Junqin, Jing, Gu, Shalev, Anath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835787/
https://www.ncbi.nlm.nih.gov/pubmed/23975026
http://dx.doi.org/10.1038/nm.3287

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835787/
https://www.ncbi.nlm.nih.gov/pubmed/23975026
http://dx.doi.org/10.1038/nm.3287

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