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Thioredoxin-interacting protein regulates insulin transcription through microRNA-204
Beta-cell dysfunction and impaired insulin production are hallmarks of diabetes(1), but despite the growing diabetes epidemic the molecular mechanisms involved have remained unclear. We identified thioredoxin-interacting protein (TXNIP), a cellular redox regulator, as a critical factor involved in b...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835787/ https://www.ncbi.nlm.nih.gov/pubmed/23975026 http://dx.doi.org/10.1038/nm.3287 |