Statistical Experimental Design Guided Optimization of a One-Pot Biphasic Multienzyme Total Synthesis of Amorpha-4,11-diene

In vitro synthesis of chemicals and pharmaceuticals using enzymes is of considerable interest as these biocatalysts facilitate a wide variety of reactions under mild conditions with excellent regio-, chemo- and stereoselectivities. A significant challenge in a multi-enzymatic reaction is the need to...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Xixian, Zhang, Congqiang, Zou, Ruiyang, Zhou, Kang, Stephanopoulos, Gregory, Too, Heng Phon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835790/
https://www.ncbi.nlm.nih.gov/pubmed/24278153
http://dx.doi.org/10.1371/journal.pone.0079650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835790/
https://www.ncbi.nlm.nih.gov/pubmed/24278153
http://dx.doi.org/10.1371/journal.pone.0079650

Ejemplares similares