A Process Similar to Autophagy Is Associated with Cytocidal Chloroquine Resistance in Plasmodium falciparum

Resistance to the cytostatic activity of the antimalarial drug chloroquine (CQ) is becoming well understood, however, resistance to cytocidal effects of CQ is largely unexplored. We find that PfCRT mutations that almost fully recapitulate P. falciparum cytostatic CQ resistance (CQR(CS)) as quantifie...

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Detalles Bibliográficos
Autores principales: Gaviria, David, Paguio, Michelle F., Turnbull, Lindsey B., Tan, Asako, Siriwardana, Amila, Ghosh, Debasish, Ferdig, Michael T., Sinai, Anthony P., Roepe, Paul D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835802/
https://www.ncbi.nlm.nih.gov/pubmed/24278114
http://dx.doi.org/10.1371/journal.pone.0079059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835802/
https://www.ncbi.nlm.nih.gov/pubmed/24278114
http://dx.doi.org/10.1371/journal.pone.0079059

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