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Discovering Subgroups of Patients from DNA Copy Number Data Using NMF on Compacted Matrices
In the study of complex genetic diseases, the identification of subgroups of patients sharing similar genetic characteristics represents a challenging task, for example, to improve treatment decision. One type of genetic lesion, frequently investigated in such disorders, is the change of the DNA cop...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835832/ https://www.ncbi.nlm.nih.gov/pubmed/24278162 http://dx.doi.org/10.1371/journal.pone.0079720 |