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Discovering Subgroups of Patients from DNA Copy Number Data Using NMF on Compacted Matrices

In the study of complex genetic diseases, the identification of subgroups of patients sharing similar genetic characteristics represents a challenging task, for example, to improve treatment decision. One type of genetic lesion, frequently investigated in such disorders, is the change of the DNA cop...

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Detalles Bibliográficos
Autores principales:	de Campos, Cassio P., Rancoita, Paola M. V., Kwee, Ivo, Zucca, Emanuele, Zaffalon, Marco, Bertoni, Francesco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835832/ https://www.ncbi.nlm.nih.gov/pubmed/24278162 http://dx.doi.org/10.1371/journal.pone.0079720

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