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Off-target effects of plasmid-transcribed shRNAs on NFκB signaling pathway and cell survival of human melanoma cells

Signal transducer and activator of transcription 3 (STAT3) and nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB) are transcription factors involved in cell survival, inflammation and metastasis. Constitutively activated STAT3 is found in many cancers, including melanoma. To study...

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Detalles Bibliográficos
Autores principales: Ramji, Kavita, Kulesza, Dorota Weronika, Chouaib, Salem, Kaminska, Bozena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835955/
https://www.ncbi.nlm.nih.gov/pubmed/24170218
http://dx.doi.org/10.1007/s11033-013-2817-7