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A Novel Method Linking Antigen Presentation by Human Monocyte-Derived Macrophages to CD8(+) T Cell Polyfunctionality

To understand the interactions between innate and adaptive immunity, and specifically how virally infected macrophages impact T cell function, novel assays examining the ability of macrophages to present antigen to CD8(+) T cells are needed. In the present study, we have developed a robust in vitro...

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Detalles Bibliográficos
Autores principales: Short, Kirsty R., Grant, Emma J., Vissers, Marloes, Reading, Patrick C., Diavatopoulos, Dimitri A., Kedzierska, Katherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835958/
https://www.ncbi.nlm.nih.gov/pubmed/24312096
http://dx.doi.org/10.3389/fimmu.2013.00389