Testing for direct genetic effects using a screening step in family-based association studies

In genome wide association studies (GWAS), family-based studies tend to have less power to detect genetic associations than population-based studies, such as case-control studies. This can be an issue when testing if genes in a family-based GWAS have a direct effect on the phenotype of interest over...

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Detalles Bibliográficos
Autores principales: Lutz, Sharon M., Vansteelandt, Stijn, Lange, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836057/
https://www.ncbi.nlm.nih.gov/pubmed/24312120
http://dx.doi.org/10.3389/fgene.2013.00243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836057/
https://www.ncbi.nlm.nih.gov/pubmed/24312120
http://dx.doi.org/10.3389/fgene.2013.00243

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