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Testing for direct genetic effects using a screening step in family-based association studies
In genome wide association studies (GWAS), family-based studies tend to have less power to detect genetic associations than population-based studies, such as case-control studies. This can be an issue when testing if genes in a family-based GWAS have a direct effect on the phenotype of interest over...
Autores principales: | Lutz, Sharon M., Vansteelandt, Stijn, Lange, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836057/ https://www.ncbi.nlm.nih.gov/pubmed/24312120 http://dx.doi.org/10.3389/fgene.2013.00243 |
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