AGO61-dependent GlcNAc modification primes the formation of functional glycans on α-dystroglycan

Dystroglycanopathy is a major class of congenital muscular dystrophy that is caused by a deficiency of functional glycans on α-dystroglycan (α-DG) with laminin-binding activity. A product of a recently identified causative gene for dystroglycanopathy, AGO61, acted in vitro as a protein O-mannose β-1...

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Detalles Bibliográficos
Autores principales: Yagi, Hirokazu, Nakagawa, Naoki, Saito, Takuya, Kiyonari, Hiroshi, Abe, Takaya, Toda, Tatsushi, Wu, Sz-Wei, Khoo, Kay-Hooi, Oka, Shogo, Kato, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836086/
https://www.ncbi.nlm.nih.gov/pubmed/24256719
http://dx.doi.org/10.1038/srep03288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836086/
https://www.ncbi.nlm.nih.gov/pubmed/24256719
http://dx.doi.org/10.1038/srep03288

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